GENERAL CATALOGUE
CDK9/10/GSK3?-IN-1
HY-151375 · 50 mg
MedChemExpress · Cat: HY-151375
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Catalog No: HY-151375
CAS No: 2423045-06-9
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
CDK9/10/GSK3?-IN-1 compound 13c is a kinase inhibitor Flavopiridol HY-10005 analogue that effectively inhibits HsGSK3? IC50=59 nM , HsCDK9/CyclinT IC50=64 nM , HsCDK5/p25 IC50=1.093 ?M and HsCDK2/CyclinA IC50=1.725 ?M . CDK9/10/GSK3?-IN-1 has anti-cancer cellular activity comparable to or higher than that of Flavopiridol. CDK9/10/GSK3?-IN-1 shows high anti-proliferative activity in vitro against up to seven cancer cell lines.