GENERAL CATALOGUE
CDK9-Cyclin T1 PPI-IN-1
HY-156296 · 50 mg
MedChemExpress · Cat: HY-156296
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medchemexpress.com/cdk9-cyclin-t1-ppi-in-1.htmlCatalog No: HY-156296
CAS No: 2995336-58-6
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
CDK9-Cyclin T1 PPI-IN-1 Compound B19 is a selective CDK9-Cyclin T1 protein-protein interaction PPI inhibitor. CDK9-Cyclin T1 PPI-IN-1 inhibits cell proliferation in TNBC MDA-MB-231 cells IC50: 0.044 ?M , and induces apoptosis. CDK9-Cyclin T1 PPI-IN-1 inhibits CDK9 transcription activity, reduces the phosphorylation of RNA Pol II CTD ser2. CDK9-Cyclin T1 PPI-IN-1 inhibits tumor growth in a TNBC 4T1 mouse model.
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