

HY-151984 · 50 mg
MedChemExpress · Cat: HY-151984
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medchemexpress.com/cdk9-in-22.htmlDescription
CDK9-IN-22 is a potent CDK9 inhibitor with IC50s of 10.4, 876.2 nM for CDK9, CDK, respectively. CDK9-IN-22 induces apoptosis and cell cycle arrests at G2/M phase. CDK9-IN-22 decreases the expression of p-RNAPII S2 and CDK9 protein. CDK9-IN-22 shows antiproliferative and aiti-tumor activity.