GENERAL CATALOGUE
CDK9-IN-7
HY-126251 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-126251
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medchemexpress.com/cdk9-in-7.htmlCatalog No: HY-126251
CAS No: 2369981-71-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CDK9-IN-7 compound 21e is a selective, highly potent, and orally active CDK9/cyclin T inhibitor IC50=11 nM , which exhibits more potent over other CDKs CDK4/cyclinD=148 nM; CDK6/cyclinD=145 nM . CDK9-IN-7 shows antitumor activity without obvious toxicity. CDK9-IN-7 induces NSCLC cell apoptosis, arrests the cell cycle in the G2 phase, and suppresses the stemness properties of NSCLC.
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