CDKN2A/p16INK4a Rabbit Monoclonal Antibody

Description

EnkiLife offers the CDKN2A/p16INK4a Rabbit Monoclonal Antibody. This antibody reacts with Mouse,Rat species and is suitable for WB,ICC/IF,IP application. Alternative Names of Immunogen: Cdkn2a;P16ink4a;Cyclin-dependent kinase 4 inhibitor A (CDK4I);p16-INK4a ;p16-INK4. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 Background: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene. Research Area: Cell Biology