CEA(CD66e) (7M6) Rabbit Monoclonal Antibody

Description

EnkiLife offers the CEA(CD66e) (7M6) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF,FC application. Alternative Names of Immunogen: adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:2000-1:20000,ICC/IF 1:200-1:500,FC 1:200-1:500 Background: Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).