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Celastramycin A
GENERAL CATALOGUE

Celastramycin A

HY-122292 · 50 mg

MedChemExpress · Cat: HY-122292

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Catalog No: HY-122292
CAS No: 188988-62-7
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

Celastramycin A is an antibiotic isolated from Streptomyces MaB-QuH-8, which exhibits antimicrobial activity against series of gram-negative bacteria and mycobacteria, with MICs between 0.05-3.1 ?g/ml. Celastramycin A exhibits immunosuppressing efficacy in ex vivo Drosophila through immune deficiency pathway IC50 of 0.008 ?g/ml , inhibits the immunoresponse in human innate immunity through TNF-? signaling, inhibits IL-8 production in HUEVCs with IC50 of 0.06 ?g/ml.

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