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Celastramycin A (isomer)
GENERAL CATALOGUE

Celastramycin A (isomer)

HY-N12905 · 1 mg

MedChemExpress · Cat: HY-N12905

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Catalog No: HY-N12905
CAS No: 491600-94-3
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress

Description

Celastramycin A isomer is an isomer of Celastramycin A HY-122292 , an antibiotic against Gram-negative bacteria and Mycobacterium tuberculosis with an MIC of 0.05-3.1 ?g/mL. Celastramycin A exerts immunosuppressive effects in Drosophila ex vivo via the immunodeficiency pathway IC50 of 8 ng/mL , inhibits human innate immune responses via the TNF-? pathway, and inhibits IL-8 production in HUEVC with an IC50 of 60 ng/mL.

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