GENERAL CATALOGUE
Cendakimab
HY-P99496 · 1 mg
MedChemExpress · Cat: HY-P99496
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Catalog No: HY-P99496
CAS No: 2151032-62-9
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Cendakimab RPC4046; ABT 308; CC-93538 is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13R?1 and IL-13R?2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases e.g., asthma and eosinophilic esophagitis .
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