GENERAL CATALOGUE
Cernuumolide J
HY-N13294 · 50 mg
MedChemExpress · Cat: HY-N13294
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medchemexpress.com/cernuumolide-j.html
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Catalog No: HY-N13294
CAS No: 2019163-02-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Cernuumolide J TMJ-105 is an JAK2/STAT3 inhibitor. Cernuumolide J induces G2/M phase arrest and apoptosis in HEL leukemia cells by downregulating the phosphorylation of JAK2, STAT3, and Erk, and activating the phosphorylation of JNK and p38 MAPK. Cernuumolide J inhibits HEL leukemia cell growth in a time- and concentration-dependent manner, with an IC50 value of 1.79 ?M. Cernuumolide J can be used for research in the field of anti-cancer therapy.
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