GENERAL CATALOGUE
CGP 12177 hydrochloride
HY-101393A · 5 mg
MedChemExpress · Cat: HY-101393A
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medchemexpress.com/cgp-12177-hydrochloride.htmlCatalog No: HY-101393A
CAS No: 64208-32-8
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
CGP 12177 AAasAasAA+/- -CGP 12177 hydrochloride is a ?-Adrenergic receptor ?-AR ligand. CGP 12177 hydrochloride is a ?3-AR Ki = 88 nM agonist with ?1/?2-AR Ki = 0.9 nM for ?1; Ki = 4 nM for ?2 antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for ?1-AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research 1 2 3 4 .
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