

HY-18211 · 50 mg
MedChemExpress · Cat: HY-18211
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medchemexpress.com/cgs-35601.htmlDescription
CGS 35601 is the inhibitor for endothelin-converting enzyme-1 ECE-1 , neutral endopeptidase 24.11 NEP , and angiotensin-converting enzyme ACE , with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 big ET-1 - and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide ANP , regulates the cardiovascular function in SD rats.







