GENERAL CATALOGUE
CH0076989
HY-136881 · 50 mg
MedChemExpress · Cat: HY-136881
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medchemexpress.com/ch0076989.htmlCatalog No: HY-136881
CAS No: 954371-52-9
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
CH0076989 is a specific CCR3 agonist. CH0076989 activates eosinophils and transfectants expressing both wild-type CCR3 and a CCR1:CCR3 chimaeric receptor lacking the CCR3 amino-terminus. CH0076989 has a direct interaction with the transmembrane helices of CCR3, supported by the complete loss of its activity due to mutations of the residues Y41, Y113 and E287. CH0076989 can be used for the study of inflammation and allergic diseases such as asthma .
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