GENERAL CATALOGUE
Ch282-5
HY-164468 · 50 mg
MedChemExpress · Cat: HY-164468
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Catalog No: HY-164468
CAS No: 65891-87-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Ch282-5 is an orally active inhibitor targeting the Bcl-2 protein, inducing mitochondria-dependent apoptosis Apoptosis by disrupting mitophagy and the mTOR pathway. Ch282-5 exhibits antiproliferative activity against colorectal cancer cells both in vitro and in vivo, and it also inhibits metastasis. Additionally, Ch282-5 enhances Oxaliplatin HY-17371 -induced autophagy Autophagy by downregulating the Mcl-1 protein and increasing platelet count, alleviating adverse effects of Navitoclax HY-10087 .
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