GENERAL CATALOGUE
CHDI-390576
HY-119939 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-119939
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medchemexpress.com/chdi-390576.htmlCatalog No: HY-119939
CAS No: 1629729-98-1
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histone deacetylase HDAC inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs 1, 2, 3 and 150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform.