

HY-N2359 · 50 mg
MedChemExpress · Cat: HY-N2359
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Manufacturer product page
medchemexpress.com/chelerythrine.html
Description
Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 ?M. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 ?M and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy.







