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CHI3L1-IN-3
GENERAL CATALOGUE

CHI3L1-IN-3

HY-175207 · 5 mg

MedChemExpress · Cat: HY-175207

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Manufacturer product page

medchemexpress.com/chi3l1-in-3.html
Catalog No: HY-175207
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress

Description

CHI3L1-IN-3 is a CHI3L1 inhibitor. CHI3L1-IN-3 binds to CHI3L1 with Kds of 13.76 ?M and 13.5 ?M in MST and SPR assays, respectively. CHI3L1-IN-3 demonstrates extended plasma half-lives and microsomal stability, along with reduced intrinsic clearance. CHI3L1-IN-3 induces dose-dependent cytotoxicity, reduces spheroid mass and inhibits migration in a 3D multicellular glioblastoma GBM spheroid model. CHI3L1-IN-3 can be used for the study of GBM.

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