Chol-CTPP

Description

Chol-CTPP is a ligand with dual targeting effect on blood-brain barrier BBB and glioma cells. Lip-CTPP can be gained by Chol-CTPP and another mitochondria targeting ligand Chol-TPP . Lip-CTPP is a promising potential carrier to exert the anti-glioma effect of doxorubicin DOX and lonidamine LND collaboratively. Lip-CTPP elevates the inhibition rate of tumor cell proliferation, migration and invasion, promote apoptosis and necrosis, and interfere with mitochondrial function.