GENERAL CATALOGUE
Cilomilast
HY-10790 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10790
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Catalog No: HY-10790
CAS No: 153259-65-5
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Cilomilast SB-207499 is a potent, selective and orally active inhibitor of Phosphodiesterase 4 PDE4 , with IC50s of 100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 IC50=74, 65, 100, and 83 ?M, respectively. Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease COPD .
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