GENERAL CATALOGUE
Cisd2 agonist 2
HY-155539 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155539
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medchemexpress.com/cisd2-agonist-2.htmlCatalog No: HY-155539
CAS No: 2916371-59-8
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Cisd2 agonist 2 compound 6 is a Cisd2 activator EC50=191 nM , and Cisd2 levels are associated with non-alcoholic fatty liver disease NAFLD . Cisd2 agonist 2 has no significant in vivo toxicity in Cisd2hKO-het mice heterozygous hepatocyte-specific Cisd2 knockout . Cisd2 CDGSH iron sulfur domain 2 is a zinc finger protein that is mainly localized in the endoplasmic reticulum or mitochondrial membrane. Cisd2 participates in mitochondrial function by forming homodimers containing two redox-active 2Fe-2S clusters.