GENERAL CATALOGUE
CKI-7 free base
HY-133028 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-133028
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Catalog No: HY-133028
CAS No: 120615-25-0
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CKI-7 free base is a potent and ATP-competitive casein kinase 1 CK1 inhibitor with an IC50 of 6 ?M and a Ki of 8.5 ?M. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 S6K1 and mitogen- and stress-activated protein kinase-1 MSK1 . CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases.
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