GENERAL CATALOGUE
CL 5343
HY-W074975 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W074975
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medchemexpress.com/cl-5343.htmlCatalog No: HY-W074975
CAS No: 14949-00-9
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CL 5343 5-Amino-1,3,4-thiadiazole-2-sulfonamide is a selective inhibitor of carbonic anhydrase B HCA-B and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 ??renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer.
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