Clarithromycin EP Impurity F

Description

12OMethyl Clarithromycin is a methylated impurity of the semisynthetic macrolide antibiotic Clarithromycin C559750 . 12OMethyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. Chen, X, et al,: Zhong, Yao,, 17, 32 2008 ; Yoshida, H, et al,: Jap, J, Antibiot,, 53, 615 2000 ; Omura, S, et al,: Yakug, Zas,, 112, 593 1992 ;