Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody

Description

EnkiLife offers the Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000 Background: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. Research Area: Cell Biology