Clindamycin-d3 hydrochloride

Description

Clindamycin-d3 hydrochloride is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations sub-MICs . Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit 23S rRNA . Clindamycin decreases the production of Panton-Valentine leucocidin PVL , toxic-shock-staphylococcal toxin TSST-1 or alpha-haemolysin Hla . Clindamycin also can be used for researching malaria.