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CLK1/2-IN-3
GENERAL CATALOGUE

CLK1/2-IN-3

HY-113831 · 1 mg

MedChemExpress · Cat: HY-113831

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Manufacturer product page

medchemexpress.com/clk1-2-in-3.html
Catalog No: HY-113831
CAS No: 1005784-60-0
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress

Description

LK1/2-IN-3 compound 3 is a potent and selective CLK1 and CLK2 inhibitor with IC50 values of 1.1, 2.1, 130, 260, 260 nM for CLK1, CLK2, SRPK1, SRPK2, SRPK3, respectively. CLK1/2-IN-3 shows anti-proliferative activity. CLK1/2-IN-3 reduces the levels of endogenous phosphorylated SR proteins and increases the expression of S6K mRNAs.

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