GENERAL CATALOGUE
CLM3
HY-164413 · 50 mg
MedChemExpress · Cat: HY-164413
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Catalog No: HY-164413
CAS No: 1312024-59-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
CLM3, a pyrazolopyrimidine derivative, is a multiple tyrosine kinase inhibitor. CLM3 shows antiproliferative and proapoptotic activity on endothelial and cancer cells, synergistically enhanced by SN38 HY-13704 . These effects are mainly due to its inhibition of phosphorylation of VEGFR-2, EGFR and RET tyrosine kinases and their related signaling pathways.
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