

HY-14539B · 50 mg
MedChemExpress · Cat: HY-14539B
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medchemexpress.com/clozapine-dihydrochloride.htmlDescription
Clozapine HF 1854 dihydrochloride is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor EC50=11 nM .







