GENERAL CATALOGUE
Clozapine
HY-14539 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14539
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Catalog No: HY-14539
CAS No: 5786-21-0
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Clozapine HF 1854 is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor EC50=11 nM .
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