GENERAL CATALOGUE
Clozapine N-oxide dihydrochloride
HY-17366A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-17366A
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medchemexpress.com/clozapine-n-oxide-dihydrochloride.htmlCatalog No: HY-17366A
CAS No: 2250025-93-3
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors DREADDs agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride cannot cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor EC50=11 nM agonist.
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