GENERAL CATALOGUE
Clozapine N-oxide dihydrochloride (Standard)
HY-17366AR · 5 mg
MedChemExpress · Cat: HY-17366AR
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Catalog No: HY-17366AR
CAS No: 2250025-93-3
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
Clozapine N-oxide dihydrochloride Standard is the analytical standard of Clozapine N-oxide dihydrochloride . This product is intended for research and analytical applications. Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors DREADDs agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier 1 2 3 4 . Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor EC50=11 nM agonist 5 6 .
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