

HY-17366R · 5 mg
MedChemExpress · Cat: HY-17366R
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Manufacturer product page
medchemexpress.com/clozapine-n-oxide-standard.html
Description
Clozapine N-oxide Standard is the analytical standard of Clozapine N-oxide. This product is intended for research and analytical applications. Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors DREADDs agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide cannot cross the blood-brain barrier 1 2 3 4 . Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor EC50=11 nM agonist 5 6 .







