GENERAL CATALOGUE
CM037
HY-110294 · 5 mg
MedChemExpress · Cat: HY-110294
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Catalog No: HY-110294
CAS No: 896795-60-1
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
CM037 is a highly selective and competitive ALDH1A1 inhibitor IC50=4.6 ?M . CM037 blocks the catalytic activity of ALDH1A1, thereby inhibiting the activation of the downstream HIF-1?/VEGF pathway. CM037 is mainly used to study the ALDH1A1-mediated regulation of cancer stem cells CSCs and angiogenesis, especially in breast cancer, showing the potential to inhibit tumor angiogenesis and stem cell characteristics.
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