

HY-172769 · 50 mg
MedChemExpress · Cat: HY-172769
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Manufacturer product page
medchemexpress.com/cm112.html
Description
CM112 is a selective protein arginine methyltransferase 1 PRMT1 degrader by tethering hydrophobic tag, adamantane, to MS023 with a 5-PEG linker. CM112 induces the degradation of PRMT1 in various solid cancer cell lines. CM112 can also target the nonenzymatic function of PRMT1 by downregulating the stability of the orphan receptor TR3. CM112 is promising for research of cancers.

