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CMP-5 dihydrochloride
GENERAL CATALOGUE

CMP-5 dihydrochloride

HY-113846A · 5 mg

MedChemExpress · Cat: HY-113846A

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Catalog No: HY-113846A
CAS No: 2309409-79-6
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress

Description

CMP-5 dihydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 dihydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 dihydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected.

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