GENERAL CATALOGUE
Cofetuzumab pelidotin
HY-P99829 · 1 mg
MedChemExpress · Cat: HY-P99829
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Catalog No: HY-P99829
CAS No: 1869937-48-3
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress
Description
Cofetuzumab pelidotin PF-06647020 is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb hu6M024, IgG1 joined to an auristatin microtubule inhibitor payload, auristatin-0101 Aur0101; HY-12522 , by a cleavable valine-citrulline vc -based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research.
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