GENERAL CATALOGUE
Conglobatin
HY-119906 · 500 g
MedChemExpress · Cat: HY-119906
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Catalog No: HY-119906
CAS No: 72263-05-9
Category: Apoptosis
Pack Size: 500 g
Brand: MedChemExpress
Description
Conglobatin FW-04-806 , a macrolide dilactone, is isolated from the culture of Streptomyces conglobatus. Conglobatin is an orally active Hsp90 inhibitor. Conglobatin can bind to the N-terminal domain of Hsp90 and disrupt Hsp90-Cdc37 complex formation. Conglobatin induces apoptosis in human breast cancer cells and esophageal squamous cell carcinoma cells, and exhibits antitumor activity in vivo.
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