GENERAL CATALOGUE
Copanlisib dihydrochloride
HY-15346A · 10 mM * 1 mL in Water
MedChemExpress · Cat: HY-15346A
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medchemexpress.com/copanlisib-dihydrochloride.htmlCatalog No: HY-15346A
CAS No: 1402152-13-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress
Description
Copanlisib dihydrochloride BAY 80-6946 dihydrochloride is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3K?, PI3K?, PI3K? and PI3K?, respectively. Copanlisib dihydrochloride has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib dihydrochloride has superior antitumor activity.
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