GENERAL CATALOGUE
Covidcil-19
HY-W728005 · 5 mg
MedChemExpress · Cat: HY-W728005
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medchemexpress.com/covidcil-19.htmlCatalog No: HY-W728005
CAS No: 1225177-95-6
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress
Description
Covidcil-19 compound C5 avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element FSE with a Kd of 11 nM. Covidcil-19 stabilizes the hairpinAAasAasAas folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation.
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