COX-1/2-IN-9

Description

COX-1/2-IN-9 Compound 3n is a potent and selective inhibitor of COX-1/2, with IC50 values of 0.031 AAasAasAAmuM and 0.01 AAasAasAAmuM, respectively. COX-1/2-IN-9 possesses both antibacterial and anti-inflammatory activities, effectively inhibiting MRSA 1478 MIC=50 ?g/mL and multidrug-resistant S. lentus MIC=50 ?g/mL . COX-1/2-IN-9 holds significant potential to alleviate MRSA-induced pneumonia in immunocompromised states.