

HY-146295 · 50 mg
MedChemExpress · Cat: HY-146295
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/cox-2-5-lox-in-2.htmlDescription
COX-2/5-LOX-IN-2 5b is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 ?M, respectively.







