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COX-2/5-LOX-IN-2
GENERAL CATALOGUE

COX-2/5-LOX-IN-2

HY-146295 · 50 mg

MedChemExpress · Cat: HY-146295

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Catalog No: HY-146295
CAS No: 2410384-59-5
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

COX-2/5-LOX-IN-2 5b is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 ?M, respectively.

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