GENERAL CATALOGUE
CPT-Se4
HY-145291 · 50 mg
MedChemExpress · Cat: HY-145291
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medchemexpress.com/cpt-se4.html
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Catalog No: HY-145291
CAS No: 2968315-03-7
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
CPT-Se4, a selenoproagent of Camptothecin CPT , shows improved potency in killing cancer cells and inhibiting tumor growth. CPT-Se4 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se4 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells IC50= 2.54-6.4 ?M .
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