GENERAL CATALOGUE
CR-1-31-B
HY-136453 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136453
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Manufacturer product page
medchemexpress.com/cr-1-31-b.htmlCatalog No: HY-136453
CAS No: 1352914-52-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A PfeIF4A with RNA. CR-1-31-B induces apoptosis of neuroblastoma and gallbladder cancer cells.
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