CRM1 Rabbit Monoclonal Antibody

Description

EnkiLife offers the CRM1 Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Research Area: Signal Transduction