GENERAL CATALOGUE
CRT0066101 dihydrochloride
HY-15698A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15698A
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medchemexpress.com/CRT0066101_dihydrochloride.htmlCatalog No: HY-15698A
CAS No: 1883545-60-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CRT0066101 dihydrochloride is a potent and orally active PKD inhibitor with IC50 values of 1 nM, 2.5 nM and 2 nM for PKD1, PKD2, and PKD3, respectively. CRT0066101 dihydrochloride is also a potent PIM2 inhibitor with an IC50 of 135.7?nM. CRT0066101 dihydrochloride exhibits anti-inflammatory activity in mice LPS HY-D1056 -induced lung injury models, and has anticancer effects.
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