GENERAL CATALOGUE
CRX-526
HY-118984 · 50 mg
MedChemExpress · Cat: HY-118984
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medchemexpress.com/crx-526.htmlCatalog No: HY-118984
CAS No: 245515-64-4
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide LPS, HY-D1056 with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-? induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model .
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