GENERAL CATALOGUE
CSC-6
HY-161072 · 50 mg
MedChemExpress · Cat: HY-161072
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medchemexpress.com/csc-6.html
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Catalog No: HY-161072
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
CSC-6 is a NLRP3 inhibitor. CSC-6 can significantly inhibit IL-1? secreted by PMATHP-1 cells with an IC50 value of 2.3 ?M. CSC-6 specifically binds NLRP3 and inhibits NLRP3 activation by blocking ASC oligomerization during NLRP3 assembly. CSC-6 effectively reduces the symptoms of NLRP3 overactivation-mediated sepsis and gout in mouse models.
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