CSF1R Mouse Monoclonal Antibody

Description

EnkiLife offers the CSF1R Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ICC,ELISA application. Alternative Names of Immunogen: FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Research Area: PI3K-Akt signaling pathway,Jak-STAT signaling pathway,Hippo signaling pathway