GENERAL CATALOGUE
CSRM617
HY-122611 · 50 mg
MedChemExpress · Cat: HY-122611
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Catalog No: HY-122611
CAS No: 787504-88-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
CSRM617 is a selective small-molecule inhibitor of the transcription factor ONECUT2 OC2, a master regulator of androgen receptor with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 is well tolerated in the prostate cancer mouse model
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