GENERAL CATALOGUE
CU-T12-9
HY-110353 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-110353
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Catalog No: HY-110353
CAS No: 1821387-73-8
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-?B and invokes an elevation of the downstream effectors TNF-?, IL-10, and iNOS.
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